Presentation of arthritogenic peptide to antigen-specific T cells by fibroblast-like synoviocytes
نویسندگان
چکیده
منابع مشابه
Presentation of arthritogenic peptide to antigen-specific T cells by fibroblast-like synoviocytes.
OBJECTIVE To assess the ability of rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLS) to function as antigen-presenting cells (APCs) for arthritogenic autoantigens found within inflamed joint tissues. METHODS Human class II major histocompatibility complex (MHC)-typed FLS were used as APCs for murine class II MHC-restricted CD4 T cell hybridomas. Interferon-gamma (IFNgamma)-treated,...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 2007
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.22573